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对６６例不同胎龄人胚胎及出生后不同年龄人肺的神经内分泌细胞（ＮＥ细胞）进行了免疫细胞化学研究。结果发现：胚胎及新生儿ＮＥ细胞比出生后要多。５－ＨＴ阳性ＮＥ细胞除存在于小支气管、细支气管上皮外，胚胎的原始肺泡壁更多见，形态多样，常有穿过基膜的突起，且能形成神经上反小体（ＮＥＢ）。而降钙素阳性ＮＥ细胞位于小支气管及细支气管，呈锥形，很少形成ＮＥＢ。结果还提示，５－ＨＴ阳性ＮＥ细胞主要作用可能是通过神感受及释放５－ＨＴ参与呼吸活动的调节。降钙素阳性ＮＥ细胞很可能是一类降钙素分泌细胞的贮备细胞。
Immunocytochemistry was performed on neuroendocrine cells (NE cells) of 66 different human embryos of different gestational ages and human lungs of different ages after birth. The results showed that: embryonic and neonatal NE cells after birth more than. In addition to being present in the bronchioles and bronchioles, the primary alveolar walls of 5-HT positive cells are more common and morphologically diverse, often with projections across the basement membrane and the formation of neuroblastoma (NEB). While calcitonin-positive NE cells located in the bronchus and bronchioles, tapered, rarely forming NEB. The results also suggest that 5-HT-positive NE cells may play a major role in the regulation of respiratory activity through the induction of 5-HT and the release of 5-HT. Calcitonin-positive NE cells are likely to be a type of reserve cells for calcitonin-producing cells.