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血浆纤维蛋白连接素(Fibronectin,FN)是来源于肝细胞和血管内皮细胞等的一种高分子糖蛋白,参与血液凝固和机体的防御等重要功能。多种疾病,尤其肝病可影响血浆FN浓度。我们对132名正常人和各型病毒性肝炎180例检测了血浆FN,发现其水平降低可反映肝病严重程度,对判断预后也有意义。现将检查结果予以分析报道。资料和方法一、病例来源本组正常人系本院血库献血员,心、肺、血、肝功能检查均正常,血清HBsAg和抗HBC均阴性。病毒性肝炎均系住院患者,年龄12～58岁,男170例,女10例。根据第二届传染病会议修订的病毒性肝炎分型诊断标准,本组急性黄疸型肝炎(急黄肝)73
Fibronectin (FN) is a kind of high molecular glycoprotein derived from hepatocytes and vascular endothelial cells, which is involved in the important functions of blood coagulation and body defense. A variety of diseases, especially liver disease, can affect plasma FN concentrations. We detected 132 normal subjects and 180 cases of various types of viral hepatitis in plasma FN, and found that the level of FN can reflect the severity of liver disease, which is also meaningful to judge the prognosis. Now check the results to be analyzed reports. Materials and Methods First, the source of the cases of normal blood donors in our hospital blood donors, heart, lung, blood and liver function tests were normal, serum HBsAg and anti-HBC were negative. Patients with viral hepatitis were hospitalized, aged 12 to 58 years, 170 males and 10 females. According to the Second Infectious Diseases Conference revised diagnostic criteria for viral hepatitis, the group of acute jaundice hepatitis (acute yellow) 73