β阻滞剂的不良反应发生率约10%,年老患者和有氮质血症者反应较多。作者遇到在服用小剂量心得宁后发生阿斯综合征1例。患者女,68岁,住院号23089,本院职工家属,因心悸、胸闷1天于1980年3月30日中午1时许一次服心得宁30毫克,3小时后出现头晕、冷汗,继即晕厥、小便失禁。作者赶至病人家中,当时神志尚清,精神萎顿,面色苍白,轻度发绀,皮肤湿冷,脉搏细弱,血压测不出,心音低钝,心率30次/分,于当日下午5时急症入院。既往无类似发作史,亦无心前区疼痛、气急及水肿史。入院体检:一般情况 Adverse reactions of beta blockers occurred in about 10% of patients, older patients and azotemia react more. The authors met with Aspen Syndrome in a small dose of experience occurred in 1 case. Female patient, 68 years old, hospitalization 23089, hospital staff members and families, due to heart palpitations, chest tightness 1 day in March 30, 1980 at noon, 1 time service experience rather 30 milligrams, 3 hours after the dizziness, cold sweat, and then syncope , Urinary incontinence. The author rushed to the patient’s home, at that time the mind is still clear, the spirit of fatigue, pale, mild cyanosis, skin wet and cold, weak pulse, blood pressure can not be measured, heart sound low blunt, heart rate 30 beats / min, . No previous history of similar attacks, no pain in the precinct, shortness of breath and history of edema. Medical examination: the general situation