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目的:对比研究5-单硝酸异山梨酯(ISMO-20)注射液与硝酸异山梨醇酯(ISOKET)注射液静脉滴注治疗心绞痛的疗效。方法:住院心绞痛患者87例,随机分为两组,ISMO-20组45例,ISOKET组42例,分别使用ISOKET注射液和ISMO-20注射液静脉滴注。参照卫生部1993年制定的《心血管系统药物临床研究指导原则》判断疗效,并进行χ2检验。结果:两组治疗后疗效均显著,两组间比较差异无显著性。结论:ISMO-20注射液与ISOKET注射液静脉滴注用于治疗心绞痛时,疗效显著,作用相似,无显著性差异。
Objective: To compare the curative effect of intravenous drip of ISMO-20 and ISOKET in the treatment of angina pectoris. Methods: A total of 87 hospitalized patients with angina pectoris were randomly divided into two groups: 45 cases in ISMO-20 group and 42 cases in ISOKET group. Intravenous infusion of ISOKET injection and ISMO-20 injection respectively. Reference to the Ministry of Health in 1993 developed “cardiovascular system drug clinical research guidelines” to determine the efficacy, and χ2 test. Results: The curative effect of both groups after treatment was significant, no significant difference between the two groups. Conclusion: The effects of ISMO-20 injection and ISOKET injection for the treatment of angina pectoris are significant and similar with no significant difference.