中国、北美和欧洲的家庭较小,需要骨髓移植(BMT)的病人只1/3或更少有组织相容性合适的亲缘供者,因此对大多数病人来说,或者选择不能治愈的方法,或者选择HLA相合的无关志愿供者骨髓移植(UD—BMT)。无关供者的选择根据人群中已知的HLA表型的个体频率,通过模拟的方法,已从理论上估计了发现HLA—A、B、DR血清型相合供者的可能性,这项研究已在白种人和东方人种中进 Families in China, North America, and Europe are smaller and require only one-third or less patients with compatible BMs for BMT, so for most patients, or to choose an incurable method , Or HLA-matched unrelated volunteer bone marrow transplantation (UD-BMT). Selection of unrelated donors The likelihood of finding HLA-A, B, DR serotype-matched donors has been theoretically estimated by means of a simulation based on the individual frequencies of known HLA phenotypes in the population In the white and oriental species into