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本文测定了32例慢性肺心病急性加重期患者血中因子Ⅷ相关抗原(ⅧR:Ag)的浓度(202.91±37.68),较正常对照组(144.72±66.17%)明显升高(P<0.01),且ⅧR:Ag 随 PaO_2 降低而升高,随 PaCO_2升高而升高。本文进一步证明慢性肺心病存在高凝状态,且与ⅧR:Ag 升高有关,为慢性肺心病在积极抗感染、氧疗等综合治疗的基础上适当加用抗凝剂,促进病情尽快缓解提供了理论依据,并为观察病情提供了一项有用的指标。本文还探讨了慢性肺心病ⅧR:Ag 升高的机理。
In this paper, we measured the concentration of factor Ⅷ R antigen (Ⅷ R: Ag) in 32 patients with acute exacerbation of chronic pulmonary heart disease (202.91 ± 37.68), which was significantly higher than that of the normal control group (144.72 ± 66.17%, P <0.01) And Ⅷ R: Ag increased with the decrease of PaO 2 and increased with the increase of PaCO 2. This article further evidence of hypercoagulability in chronic pulmonary heart disease, and with â ... § R: Ag is elevated, for chronic pulmonary heart disease in the active anti-infection, oxygen therapy and other comprehensive treatment based on the appropriate use of anticoagulants, and promote the alleviation of the disease provided Theoretical basis, and to observe the condition provides a useful indicator. This article also explored the pathogenesis of chronic cor pulmonale Ⅷ R: Ag.