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银屑病是一种常见的慢性炎症性皮肤病，其病因不明、发病机制不清，病情易反复发作，严重影响患者的生活质量。辅助性 T 细胞17（Th17）是新发现的一类免疫细胞，由 CD4＋T 细胞受一些炎性细胞因子网刺激分化而来。近年来更多的研究表明， Th17细胞相关细胞因子在银屑病的发病机制中发挥重要作用，其中白细胞介素（ IL）23可促进 Th17诱发银屑病皮损形成，IL－22和 IL－17也参与了该过程的众多炎症反应。该文就 Th17细胞相关细胞因子与银屑病的研究进展予以综述。“,”Psoriasis is a kind of common chronic inflammatory skin disease,the etiology and pathogenesis of which is still unknown,but the disease is easy to recur,seriously affecting the quality of life of the patients.Th17 cells are newly discovered immune cells, developed from CD4 +T cells under the influence of a network of inflammatory cytokines.IL-23,which promotes Th17 cell development,as well as IL-22 and IL-17 produced by the Th17 cells play essential roles in various inflammatory diseases.In recent years,more studies illustrate Th17-related cytokines play a critical role in the pathogenesis of psoriasis.Here is to make a review of the research progress of Th17 related cytokines and psoriasis.