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1 对象和方法1.1 对象全部病例均符合1990年(上海)第六次全国病毒性肝炎学术会议修订的诊断标准。血清胆红素(SB)均>345mmol/L。84例患者中,男60例,女24例;年龄14岁～77岁,60岁以上15例,平均年龄43岁。全部病例均有程度不同的消化道症状及凝血酶原时间(PT,正常值13S)均延长4S以上,其中36例延长达正常值的一倍以上。肝促凝血活酶(HPT,正常值80%以上)<30%占30例。血清白蛋白(A)均<40g/L,其中36例<30g/L。尿素氮(BUN)>7.2mmol/L30
1 Subjects and methods 1.1 All subjects were in line with the 1990 (Shanghai) Sixth National Viral Hepatitis Conference revised diagnostic criteria. Serum bilirubin (SB)> 345mmol / L. 84 patients, 60 males and 24 females; aged 14 to 77 years old, 15 years old 60 years of age, mean age 43 years. All cases had varying degrees of gastrointestinal symptoms and prothrombin time (PT, normal 13S) were extended 4S above, of which 36 cases extended to more than double the normal value. Hepatic thromboplastin (HPT, more than 80% of normal) <30% 30 cases. Serum albumin (A) were <40g / L, of which 36 cases <30g / L. Urea nitrogen (BUN)> 7.2mmol / L30