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一、引言 绒毛膜癌及葡萄胎来源于胎盘滋养叶母细胞,不论从原因、发病率、年龄分布、病理形态学、临床表现、生物学行为以及治疗、予后等方面,均具有非常独特的性质。构成肿瘤学中极为特殊的一类,长久以来,一直为妇产科医师及病理工作者所重视,已积累了大量的文献资料,在我国尤其常见。解放以来全国各地对这类疾病的分析统计、观察研究的论著很多。然而,对于其分类命名、绒毛膜癌与葡萄胎之关系、病理诊断等问题还存在一些不同的看法,对于其发生原因及发病机理大多尚停留于推断。我们根据形态学观察,结合文献复习及自己的体会,愿对滋养叶母细胞发生的肿瘤在性质特点、病理学诊断、转移、分类、命名、发病原因方面作初步探讨,提出粗浅的看法,希同道们展开争鸣与批评指正。
I. Introduction Choriocarcinoma and hydatidiform mole originate from the placental nourishloblastoma and have unique characteristics in terms of cause, incidence, age distribution, pathomorphology, clinical manifestation, biological behavior, treatment and prognosis nature. Formed a very special category of oncology, for a long time, has been for gynecologists and pathologists attention, has accumulated a large number of documents, especially in our country. Since the liberation of all parts of the country the analysis of such diseases statistics, observational research a lot. However, there are some different opinions on the classification and naming of choriocarcinoma, the relationship between choriocarcinoma and hydatidiform mole, the pathological diagnosis and so on. Most of its causes and pathogenesis remain inferred. According to morphological observation, combined with literature review and their own experience, we would like to make preliminary discussions on the characteristics of nodules, pathological diagnosis, metastasis, classification, naming, Fellow comrades start arguing and criticizing.