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以往对乙脑的治疗,主要为对症处理,我科于1988～1989年7～9月收治的11例乙脑患者,在综合治疗的基础上,加用本校微生物学教研室采用淋巴细胞杂交瘤技术生产鼠源性高中和活性JEV-McAb早期抢救性治疗,收到明显疗效。 治疗组11例,对照组11例,入院后给予物理降温、镇静剂。甘露醇脱水综合治疗。治疗组五病日内给JEV-McAb静脉滴注1次,小儿5mg, 成人10mg 用药前做皮肤过敏试验,阴性者方使用。 治疗组入院治疗后在退热时间,昏迷、颈项强直、肌张力增强恢复时间比对照组明
The treatment of JE in the past mainly for symptomatic treatment, our department from 1988 to 1989, 7 to 9 months admitted to 11 cases of JE patients, on the basis of comprehensive treatment, plus the Department of Microbiology using lymphocyte hybridoma technology Production of murine high school and active JEV-McAb early rescue treatment, received significant effect. 11 cases in the treatment group and 11 cases in the control group were given physical cooling and sedation after admission. Mannitol dehydration comprehensive treatment. The treatment group five days to intravenous injection of JEV-McAb 1, pediatric 5mg, 10mg adult skin allergy test before use, the negative side to use. Treatment group admission treatment in the antipyretic time, coma, neck stiffness, muscle tone enhancement recovery time than the control group