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目的了解广西1989-2008年传统可免疫性疾病发病率和死亡率的时间序列特征,为制定广西计划免疫工作措施提供参考依据。方法收集广西1989-2008年传统可免疫性疾病的疫情资料,对该地区传统可免疫性疾病的流行趋势和特征进行统计学描述。结果广西1989-2008年共发生传统可免疫性疾病1 191 789例,死亡5 382例,年均发病率为124.29/10万,年均死亡率为0.53/10万;广西1989-2008年传统可免疫性疾病的疾病谱发生改变,从1989年发病率最高的乙肝(3.02/10万)转为2008年的肺结核(131.41/10万);发病率时间序列分布表明,广西1989-2008年乙肝、肺结核的发病率呈上升趋势,麻疹在1993年出现1次暴发后递减,新生儿破伤风、百日咳、白喉和脊髓灰质炎总体呈下降趋势;广西1989-2008年传统可免疫性疾病的死亡谱发生改变,1989-2003年新生儿破伤风死亡率居于7种疾病的首位,2004-2008年死亡率居于首位的疾病转变为肺结核;死亡率时间序列分布表明,广西1989-2008年传统可免疫性疾病总体死亡率呈明显下降趋势(1993年除外),麻疹、脊髓灰质炎、白喉、百日咳和新生儿破伤风死亡率呈下降趋势,但肺结核和乙肝死亡率总体呈上升趋势。结论广西1989-2008年麻疹、新生儿破伤风、百日咳、白喉和脊髓灰质炎的发病率及死亡率呈下降趋势,乙肝和肺结核的发病率和死亡率呈上升趋势。
Objective To understand the time series features of incidence and mortality of traditional immunological diseases in Guangxi from 1989 to 2008 and provide reference for the formulation of measures for immunization in Guangxi. Methods Epidemic data of traditional immunological diseases in Guangxi from 1989 to 2008 were collected to describe the epidemiological trends and characteristics of traditional immunological diseases in the area. Results A total of 1 191 789 cases of traditional immunocompromised diseases occurred in Guangxi from 1989 to 2008, with 5 382 deaths, the annual average incidence was 124.29 / 100 000 and the annual average death rate was 0.53 / 100 000. The disease spectrum of immune diseases changed from the highest incidence of hepatitis B (3.02 / 100,000) in 1989 to that of 2008 (131.41 / 100,000). The time series distribution of incidence showed that in Guangxi in 1989-2008, hepatitis B, The incidence of tuberculosis was on the rise. Measles dropped after one outbreak in 1993. The incidence of neonatal tetanus, whooping cough, diphtheria and poliomyelitis tended to decline. The death spectrum of traditional immunocompromised diseases in Guangxi during 1989-2008 Change, from 1989 to 2003 neonatal tetanus mortality ranked first in the seven diseases, the highest death rate in 2004-2008 into tuberculosis disease; time series of mortality shows that the Guangxi 1989-2008 traditional immunological diseases The overall mortality rate showed a significant downward trend (except in 1993). The mortality rates of measles, poliomyelitis, diphtheria, whooping cough and neonatal tetanus showed a downward trend, but the overall mortality rate of tuberculosis and hepatitis B was on the rise. Conclusions The incidence and mortality rates of measles, neonatal tetanus, whooping cough, diphtheria and poliomyelitis in Guangxi from 1989 to 2008 are on the decline. The incidence and mortality of hepatitis B and tuberculosis are on the rise.