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目的对临床支气管炎和肺炎患者治疗中血清降钙素原和C-反应蛋白进行研究分析。方法选取2012年1月—2013年10月治疗的支气管炎和肺炎患者各100例,作为研究对象。根据患者的病症分为支气管炎组和肺炎组。对两组患者治疗前后的PCT和CRP进行测定,并比较分析其结果。结果①两组患者治疗前其CRP和PCT水平均有明显升高,治疗后也均有所降低;②肺炎组患者其治疗前后CRP和PCT水平的变化均高于支气管炎组患者,且P<0.05,差异具有统计学意义;③支气管炎组患者治疗前PCT水平变化较CRP水平变化更具有特异性。结论CRP和PCT在支气管炎和肺炎患者治疗前呈现升高,而治疗后下降的特征,其中肺炎患者变化更加显著,而PCT水平在支气管炎组中表现突出,可作为支气管炎发作的特异性指标检测。
Objective To study the serum procalcitonin and C-reactive protein in the treatment of patients with clinical bronchitis and pneumonia. Methods 100 patients with bronchitis and pneumonia who were treated from January 2012 to October 2013 were selected as the study subjects. According to the patient’s illness is divided into bronchitis group and pneumonia group. The PCT and CRP before and after treatment were measured in both groups, and the results were compared and analyzed. Results ① The levels of CRP and PCT in both groups were significantly increased before treatment and also decreased after treatment. ② The changes of CRP and PCT in patients with pneumonia before and after treatment were significantly higher than those in patients with bronchitis, and P < 0.05, the difference was statistically significant; ③ bronchitis patients before treatment PCT level changes more specific than CRP level changes. Conclusions CRP and PCT were elevated in patients with bronchitis and pneumonia before treatment, but decreased after treatment. The changes of pneumonia patients were more significant, while PCT levels were prominent in bronchitis group, which could be used as a specific index of bronchitis attack Detection.