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目的：探讨沙丁胺醇联合布地奈德治疗小儿哮喘急性发作的临床疗效。方法将100例临床确诊的哮喘急性发作期的儿童随机分为对照组与治疗组，对照组在常规的改善通气等治疗基础上采用沙丁胺醇雾化吸入等治疗，治疗组常规治疗基础上采用沙丁胺醇联合布地奈德雾化吸入治疗，观察两组症状体征改善及治疗效果。结果治疗组总有效率为96%，对照组总有效82%，治疗组总有效率明显优于于对照组（P＜0.05）。结论采用沙丁胺醇联合布地奈德治疗小儿喘息急性发作效果好，值得临床上进一步推广。“,”Objective:To investigate the clinical ef icacy of salbutamol combined with budesonide in treatment of acute at ack of asthma in children. Methods: 100 patients with acute asthma were randomly dividedtime into control group and treatment group, the control group in the conventional treatment on the basis of the improved ventilation and inhaled salbutamol treatment, the treatment groupbased on conventional treatment using salbutamol combined withbudesonide atomization inhalation treatment, the two groups were observed and the improvement of symptoms and signs ef ect of treatment. Results: the total ef ective rate of treatment group was 96%, control group total ef ectiveness 82%, the total ef ective rate of treatment group was bet er than in the control group (P< 0.05). Conclusion: the use of salbutamol and budesonide treatment of children with acute asthmatic at ack ef ect is good, it is worth popularizing in clinical.