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目的观察急性溴甲烷中毒患者对神经系统损害的后遗症状。方法对６例急性溴甲烷中毒病人的临床资料进行分析，并对１例重度中毒病人进行了３年追踪观察。结果急性溴甲烷中毒患者的临床表现以中枢神经系统损害为主，在重度中毒的病人可伴发周围神经损害。本组病人潜伏期为５～１０ｄ，潜伏期过后，相继出现中毒症状和体征。重度中毒病人可导致中枢神经系统功能障碍和神经系统症状、体征恢复不完全。结论急性溴甲烷重度中毒患者可遗留共济失调、锥体束损害等神经系统后遗症。
Objective To observe the symptoms of neurotoxicity in patients with acute methyl bromide poisoning. Methods The clinical data of 6 cases of acute methyl bromide poisoning were analyzed. One case of severe poisoning was followed up for 3 years. Results The clinical manifestations of acute methyl bromide poisoning in the central nervous system damage mainly in patients with severe poisoning may be associated with peripheral nerve damage. The incubation period of patients in this group is 5 ~ 10d, after the incubation period, one after another poisoning symptoms and signs. Patients with severe poisoning can lead to central nervous system dysfunction and neurological symptoms, signs of incomplete recovery. Conclusion Patients with acute methyl bromide poisoning may suffer from ataxia, pyramidal tract damage and other neurological sequelae.