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近20年由于免疫学、细胞化学等的重大进展,肾活检、荧光技术和电镜的普遍应用,人们对肾小球疾病的病因学和发病学有了较明确的认识。本文着重综述肾小球疾病发病机理若干问题。一、肾小球疾病非免疫性发病机理最近不少学者报道了有关非免疫性肾小球损伤的发病机理在发病学上的重要作用。Baldwin认为肾小球进行性损伤是受多种非免疫因素的影响。 1.肾内血管病变作者认为肾内血管病变可能为肾小球疾病的原发因素。 Kincaid-Smith报道在40岁以下,血压在
Nearly 20 years due to immunology, cytochemistry and other major advances, renal biopsy, fluorescence and electron microscopy universal application, people have a clear understanding of the etiology and pathogenesis of glomerular diseases. This article focuses on a number of problems in the pathogenesis of glomerular diseases. First, the non-immune glomerular disease pathogenesis Recently, many scholars reported on the pathogenesis of non-immune glomerular injury in the pathogenesis of an important role. Baldwin believes that glomerular progressive damage is affected by a variety of non-immune factors. 1. Renal vascular disease The author believes that renal vascular disease may be the primary factor in glomerular disease. Kincaid-Smith reports that blood pressure is below 40 years of age