Abstract [Oh.jective] The aim was to study on effects of heavy metals and saline-al- kali on growth, physiology and biochemistry of Orychophragmus violaceus. [Method] Taken Orychophragmus violaceus as materials, growth, physiology and biochemistry were explored under stress of saline-alkali and heavy metals （light, moderate and se- vere saline-alkali, Pb, Pb ＋ Cd, light saline-alkali ＋ Pb, moderate saline-alkali ＋ Pb, severe saline-alkali ＋ Pb, light saline-alkali ＋ Pb ＋ Cd, moderate saline-alkali ＋ Pb ＋ Cd and severe saline-alkali ＋ Pb ＋ Cd） with control group set. [Result] Light stress of saline-alkali had little effect on membrane permeability, as follows： MDA contents in leaves and root systems declined by 25.6% and 9.0% compared with control group; Pb （500 mg/L） stress promoted synthetization of photosynthetic pigments, as follows： chlorophyll a and b and carotenoid increased by 0.86%, 0.69% and 6.25% than those of control group; combined stresses of Pb and Cd destroyed synthetization of photosynthetic pigments, among which carotenoid was more sensitive; under com- bined stresses of saline-alkali, Pb and Cd, POD and SOD activities, soluble saccha- rides and Pro content all increased and activities of POD and SOD in root system were both higher than those in leaves. [Conclusion] Orychophragmus violaceus is with resistance against light combined stresses of saline-alkali and Pb （500 mg/L）.