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一般认为局限性胃癌病人的生存期是10个月。切除原发瘤和区域淋巴结、使切缘无肿瘤存在(姑息性切除),已成为最有效的治疗方法。施行姑息性切除的胃癌病人生存期为24个月,其5年生存率约20%,一项试验性研究证明,施行手术前2个疗程及术后3个疗程的化疗是可行的。另有研究报告,不能切除的晚期胃癌病人应用鬼臼乙叉甙、阿霉素和顺铂联合化疗,临床病理上证实有良好效应的占15%。
It is generally believed that the survival of patients with localized gastric cancer is 10 months. The removal of primary tumors and regional lymph nodes and the presence of tumors at the margins (palliative resection) have become the most effective treatment. The survival period of patients with palliative resection for gastric cancer is 24 months, and the 5-year survival rate is about 20%. A pilot study has demonstrated that it is feasible to perform two courses of chemotherapy before surgery and three courses of chemotherapy after surgery. Another study reported that patients with unresectable advanced gastric cancer were treated with etoposide, doxorubicin, and cisplatin combined with chemotherapy, and the clinical pathology proved to have a good effect of 15%.