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目的 :探讨两种不同的质子泵抑制剂雷贝拉唑 (波利特 )及奥美拉唑 (洛赛克 )的七日疗效。方法 :根据临床症状和胃镜检查结果 ,将 43例十二指肠球部溃疡病人随机分组 ,试验组雷贝拉唑 10mg d ,对照组奥美拉唑 2 0mg d ,记录服药前后病人上腹痛、反酸、上腹烧灼感症状积分的改变 ,按积分下降值判定疗效。结果 :雷贝拉唑、奥美拉唑两组病人服药一周后积分下降分别为 3 43± 0 74,3 3 7± 0 78,下降率分别为 72 % ,74% ,两者均有明显下降 ,并两者比较差异无显著性。结论 :雷贝拉唑对十二指肠球部溃疡疗效与奥美拉唑相似。
Objective: To investigate the effect of two different proton pump inhibitors rabeprazole (Pollitazone) and omeprazole (Losec) on the seventh day. Methods: According to clinical symptoms and gastroscopy, 43 cases of duodenal ulcer patients were randomly divided into experimental group rabeprazole 10mg d, the control group omeprazole 20mg d, recorded before and after treatment of patients with abdominal pain, Acid reflux, abdominal burning sensory changes in the points, according to the value of the decline points to determine the efficacy. Results: After a week of taking rabeprazole and omeprazole, the integral decline was respectively 3 43 ± 0 74 and 33 7 ± 0 78, the decreasing rates were 72% and 74%, respectively, both of which decreased significantly , And no significant difference between the two. Conclusion: Rabeprazole has similar efficacy to omeprazole in duodenal ulcer.