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环境内分泌干扰物是指能干扰机体天然激素(雌激素、雄激素或甲状腺素等)的合成、分泌、转运、结合、作用或清除等,从而对生物和人类的生殖、神经和免疫系统等的功能产生影响的各种外源物质,其中有一大类物质,具有雌激素样活性,可模拟内源性雌激素的生理、生化作用,具有拮抗雄激素的效应,称为环境雌激素。环境雌激素可增加雌激素反应组织的肿瘤发生率,对妇科肿瘤如卵巢癌、子宫肿瘤等的发生发展也有促进作用。
Environmental endocrine disruptors are those that can interfere with the synthesis, secretion, transport, binding, action or elimination of the natural hormones (estrogen, androgens, or thyroxine, etc.) in the body and thus on the reproductive, nervous and immune systems of humans and humans Function of a variety of foreign substances, including a large group of substances, with estrogen-like activity, can simulate the physiological and biochemical effects of endogenous estrogen, antagonistic androgen effect, known as the environmental estrogen. Environmental estrogen can increase the incidence of estrogen response to tumor tissue, gynecological tumors such as ovarian cancer, uterine tumors also have the role of the occurrence and development.