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目的:对甲氧氯普胺治疗偏头痛的临床价值进行分析。方法:选取62例偏头痛患者,按照治疗方法将其分为两组(各31例),观察组给予甲氧氯普胺治疗,对照组给以赖氨匹林治疗,比较治疗效果。结果:观察组患者临床治疗总有效率93.55%显著高于对照组患者70.97%,观察组患者治疗后血浆内皮素水平显著低于对照组和治疗前的,且观察组患者治疗后高切全血黏度、低切全血黏度、血浆黏度、血小板黏附率、纤维蛋白原、红细胞沉降率和血细胞比容均显著低于对照组和治疗前,差异具有统计学意义(P<0.01)。结论:在治疗偏头痛临床上甲氧氯普胺效果显著,提高患者生活质量。
Objective: To analyze the clinical value of metoclopramide in the treatment of migraine. Methods: Sixty-two migraineurs were selected and divided into two groups (31 in each group) according to the method of treatment. Metoclopramide was given to the observation group and to the paracetamol in the control group. The treatment effect was compared. Results: The total effective rate of clinical observation in observation group was 93.55%, which was significantly higher than that in control group (70.97%). The plasma endothelin level in observation group was significantly lower than that in control group and before treatment, Viscosity, low cut whole blood viscosity, plasma viscosity, platelet adhesion rate, fibrinogen, erythrocyte sedimentation rate and hematocrit were significantly lower than the control group and before treatment, the difference was statistically significant (P <0.01). Conclusion: Metoclopramide is effective in the treatment of migraine and improves the quality of life of patients.