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目的了解志丹县健康人群麻疹、风疹、流行性腮腺炎(腮腺炎)抗体水平,为制定预防控制策略提供科学依据。方法采用分层随机抽样抽取志丹县健康人群280人,分为<1岁、1~2岁、3~4岁、5~6岁、7~14岁、15~19岁和≥20岁7个年龄组,每组随机抽取40人,采集血清;采用酶联免疫吸附试验法(enzyme-linked immunosorbent assay,ELISA)检测麻疹、风疹、腮腺炎IgG抗体,同时调查其患病史、免疫史及人口学特征。结果麻疹、风疹和腮腺炎抗体阳性率分别为94.64%、80.71%和57.50%;抗体几何平均浓度(geometric mean concentration,GMC)分别为2 702.89 IU/L、177.48 IU/L和350.28 U/L。结论麻疹抗体阳性率高于风疹、腮腺炎抗体阳性率,0~19岁腮腺炎抗体阳性率随着年龄的增加而逐渐升高,接种疫苗可以显著提高抗体水平,应继续加强儿童麻风疫苗和麻腮风疫苗接种。
Objective To understand the levels of measles, rubella and mumps antibody in healthy population in Zhidan County and provide a scientific basis for making prevention and control strategies. Methods A total of 280 healthy people in Zhidan County were sampled by stratified random sampling and divided into three groups: one year old, one to two years old, three to four years old, five to six years old, seven to 14 years old, 15 to 19 years old and ≥20 years old 7 Age group, each group randomly selected 40 people, serum was collected; measles, rubella and mumps IgG antibodies were detected by enzyme-linked immunosorbent assay (ELISA), at the same time to investigate the history, immunization history and Demographic characteristics. Results The positive rates of measles, rubella and mumps were 94.64%, 80.71% and 57.50%, respectively. The geometric mean concentrations (GMCs) of antibodies were 2 702.89 IU / L, 177.48 IU / L and 350.28 U / L, respectively. Conclusion The positive rate of measles antibody is higher than the positive rate of rubella and mumps antibody. The positive rate of mumps antibody from 0 to 19 years is increasing with the increase of age. Vaccination can significantly increase the antibody level, and the leprosy vaccine and hemp should continue to be strengthened. Mumps vaccination.