论文部分内容阅读
目的观察补肾益髓方对白血病化疗患者毒副作用的影响。方法选择我院行化疗的白血病患者90例采用随机数字表法分为观察组和对照组,对照组给予单纯化疗,观察组在对照组基础上给予补肾益髓方治疗,记录两组化疗期间毒副反应情况。结果观察组治疗后白细胞计数(3.97±1.45)×109/L,血小板计数(145.28±60.37)×109/L;对照组治疗后白细胞计数(2.64±1.01)×109/L,血小板计数(109.74±44.23)×109/L;组间比较差异有统计学意义(P<0.05)。观察组发生恶心呕吐11例,脱发6例,出血2例,口腔炎5例,肝功能损伤8例;对照组发生恶心呕吐24例,脱发17例,出血9例,口腔炎15例,肝功能损伤19例;组间比较差异有统计学意义(P<0.05)。结论补肾益髓方可降低白血病化疗患者毒副反应发生率,减轻化疗药物产生的毒性,提高患者对化疗耐受性,值得在临床上推广使用。
Objective To observe the effect of Bushen Yisui Fang on toxic and side effects of chemotherapy in patients with leukemia. Methods Ninety patients with leukemia who underwent chemotherapy in our hospital were divided into observation group and control group by random number table. The control group was given chemotherapy alone. The observation group was given Bushen Yisui Fang treatment on the basis of control group. Side effects. Results The white blood cell count (3.97 ± 1.45) × 109 / L and the platelet count (145.28 ± 60.37) × 109 / L in the observation group after treatment were 2.64 ± 1.01 × 109 / L and 109.74 ± 44.23) × 109 / L; there was significant difference between the two groups (P <0.05). In the observation group, nausea and vomiting occurred in 11 cases, hair loss in 6 cases, bleeding in 2 cases, stomatitis in 5 cases and liver injury in 8 cases. In the control group, nausea and vomiting occurred in 24 cases, hair loss in 17 cases, bleeding in 9 cases, stomatitis in 15 cases, 19 cases were injured, the difference between the two groups was statistically significant (P <0.05). Conclusion Bushen Yisui Decoction can reduce the incidence of toxic and side effects of chemotherapy in patients with leukemia, reduce the toxicity of chemotherapy drugs, and improve patient tolerance to chemotherapy, which is worth popularizing in clinic.