人类各种疾病中血清总补体或单一成分含量可发生变化,因此,补体水平测定或组织定位观察对某些疾病诊断具有一定意义。有的实验表明,在矽肺动物模型大鼠肺巨噬细胞表面C_3受体增加,并有促进吞噬功能的现象,有人测定矽肺和煤矽肺病人外周血中补体C_3含量显著增高,但也有报道矽肺和煤矽肺病人血清补体C_3水平变化 Serum total complement or single component content in various human diseases can change, therefore, complement level determination or tissue location observation of certain diseases is of some significance. Some experiments show that in the silicosis animal model rat lung macrophages surface C_3 receptor increased and promote phagocytosis phenomenon, it was determined silicosis and coal silicosis peripheral blood complement C_3 content was significantly increased, but there are also reports of silicosis and Change of Serum Complement C_3 in Patients with Coal Silicosis