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应用自体及同种异体ＬＡＫ细胞对２组晚期原发性肝癌患者进行治疗。结果示治疗后２组患者外周血ｍＩＬ－２Ｒ表达阳性率、ＮＫ细胞活性及ＣＤ４／ＣＤ３比值均较治疗前显著升高，血清ｓＩＬ－２Ｒ会量则较治疗前降低，提示机体免疫功能得到明显提高。两种不同来源ＬＡＫ细胞在改善肝癌患者免疫功能上无明显差异。显示胚胎胸腺与脾脏亦是理想ＬＡＫ前体细胞的来源之一。
Autologous and allogeneic LAK cells were used to treat 2 patients with advanced primary liver cancer. The results showed that the positive rate of mIL-2R expression, NK cell activity, and CD4/CD3 ratio in the peripheral blood of the two groups after treatment were significantly higher than before treatment, and the serum sIL-2R level was lower than before treatment, suggesting that the body’s immune function was significantly improved. improve. Two different sources of LAK cells did not significantly improve the immune function of patients with liver cancer. It is also shown that embryonic thymus and spleen are also one of the sources of ideal LAK precursor cells.