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目的对丙泊酚联合瑞芬太尼对疼痛患者的疗效及机制的探讨。方法选择用我院2012年12月~2014年12月接诊的80例疼痛病患者进行研究，根据随机数表法分常规组和对照组各40例，常规组采用日常的治疗方案，对照组采用丙泊酚联合瑞芬太尼进行治疗。对比两组患者的疗效及机制分析。结果治疗后，对照组的疼痛治疗状况明显好于常规组，常规组治疗有效为32例，总有效率为80%，对照组的治疗有效为39例，总有效率为97.5%，对照组的无效为1例，占总比例的2.50%，两组比较有显著性差异(=3.2373，=0.0012)。结论丙泊酚联合瑞芬太尼对疼痛患者的临床疗效显著，值得广泛推广与应用。“,”Objective To investigate the curative ef ect and mechanism of propofol combined with remifentanil in patients with pain.Methods 80 cases of patients with pain were selected in our hospital from December,2012 to December,2014,80 patient admissions,according to the random number table method,they were divided into routine group and the control group of 40 people,the routine group were treated with routine scheme,the control group using remifentanil combined with propofol for treatment.Analysis of therapeutic ef ect and mechanism of the two groups were compared.Results After the treatment,the condition of pain treatment group was obviously bet er than that of conventional treatment group,the ef ective number of conventional group was 32,the total ef iciency was 80%,have ef ective treatment and control group was 39,the total ef ective rate was 97.5%,the invalid number of control group was one,accounted for the proportion of the total number of 2.50%and the two group were significant dif erence(u=3.2373, =0.0012).Conclusion The clinical ef icacy of propofol combined with remifentanil in patients with pain significantly,it is worthy of popularization and application.