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目的观察大蒜素联合抗结核药物治疗肺结核的疗效及其副作用。方法对32例肺结核患者采用大蒜素肠溶胶丸和抗结核药物治疗,16例患者单用抗结核药物作为对照组治疗,治疗2个月后观察疗效,记录副作用。碱性磷酸酶-抗碱性磷酸酶(APAAP)方法检测淋巴细胞免疫状况。结果治疗组痰转阴率,症状改善率明显高于对照组。肝功能损伤发生率与对照组无明显差异。治疗2个月后,细胞免疫指标CD3、CD4、CD4/CD8较治疗前提。结论大蒜素肠溶胶丸联合抗结核药物治疗肺结核可提高成功率,增强细胞免疫功能。
Objective To observe the curative effect and side effects of allicin combined with antituberculosis drugs in the treatment of pulmonary tuberculosis. Methods 32 cases of tuberculosis patients were treated with allicin enteric-coated capsules and anti-tuberculosis drugs, 16 patients were treated with anti-tuberculosis drugs alone as control group. After 2 months of treatment, the curative effect was observed and side effects recorded. Alkaline phosphatase - alkaline phosphatase (APAAP) method to detect lymphocyte immune status. Results The treatment group sputum negative conversion rate, the rate of improvement was significantly higher than the control group. The incidence of liver injury and control group no significant difference. After 2 months of treatment, the cellular immune indicators CD3, CD4, CD4 / CD8 than the treatment. Conclusion Allicin enteric-coated capsules combined with anti-tuberculosis drugs can improve the success rate and enhance cellular immune function.