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目的探讨急性有机磷中毒继发阿托品中毒呼吸衰竭的发病原因,临床特点,救治方法及预防措施。方法回顾性分析1999年6月至2005年6月收治的急性有机磷中毒继发阿托品中毒呼吸衰竭17例患者的临床资料。结果 17例患者中4例阿托品化表现不典型,3例接触性中毒患者,阿托品初始剂量过大,2例双眼被农药污染,6例已给于负荷量的解磷注射液,对阿托品中毒认识不足,继续使用阿托品使中毒逐渐加重而导致呼吸衰竭。结论阿托品中毒在急性有机磷中毒抢救中是比较常见的,其主要原因是没有正确理解阿托品化的含义,对阿托品中毒认识不足,只要不片面追求使用大剂量阿托品,阿托品中毒呼吸衰竭是完全可以避免的。
Objective To investigate the etiological factor, clinical features, treatment and prevention of respiratory failure caused by acute aphthous poisoning caused by atropine poisoning. Methods The clinical data of 17 patients with respiratory failure secondary to atropine poisoning admitted to our hospital from June 1999 to June 2005 were retrospectively analyzed. Results Among the 17 patients, 4 cases had atypical atropisation, 3 cases had contact poisoning, the initial dose of atropine was too large, 2 cases of eyes were contaminated with pesticides, and 6 cases were given the loading dose of Phosphate-Aminotrophic Injection. Insufficient, continue to use atropine poisoning gradually lead to respiratory failure. Conclusion Atropine poisoning in acute organophosphate poisoning rescue is more common, the main reason is not correctly understand the meaning of atropine, lack of understanding of atropine poisoning, as long as the one-sided pursuit of high-dose atropine, atropine poisoning respiratory failure can be completely avoided of.