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副溶血性弧菌是导致我国细菌性食物中毒事件的首要原因。临床分离株和环境分离株的病原学特征有着明显的差异。临床分离株以O3∶K6血清型为主,tdh和(或)trh基因携带率较高,一般在80%以上,脉冲场凝胶电泳(PFGE)基因图谱具有明显的优势图谱,并且与血清分型具有一致性。而环境分离株(包括食品)多无优势血清型和优势PFGE图谱,tdh和(或)trh基因携带率远低于临床分离株,多在6%以下。各地临床分离株的耐药性差异较大,但对氨苄西林等早期药物耐药率均较高。环境分离株较临床分离株的耐药性更为严重和复杂。
Vibrio parahaemolyticus is the leading cause of bacterial food poisoning in China. The etiological characteristics of clinical isolates and environmental isolates have obvious differences. The clinical isolates were predominantly O3: K6 serotypes with high prevalence of tdh and / or trh genes, typically over 80%, and the PFGE genotypes had a clear predominance pattern and were associated with serum levels Consistency. However, there were no dominant serotypes and predominant PFGE profiles in environmental isolates (including food). The carrying rates of tdh and / or trh genes were much lower than those of clinical isolates, mostly below 6%. Drug resistance varied widely among clinical isolates, but rates of resistance to early drugs such as ampicillin were high. Environmental isolates more clinical isolates of drug resistance is more serious and complex.