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自1940年以来,报告的破伤风病例发生率和破伤风相关死亡率就在逐步减少。这首先应归功于破伤风类毒素的接种[即儿童白喉、破伤风类毒素和全细胞百日咳疫苗(DTP),儿童白喉、破伤风类毒素和无细胞百日咳疫苗(DTaP),儿童白喉和破伤风类毒素(DT),以及成人破伤风和白喉类毒素(Td)]。然而,改进创口管理和接生操作同样也引起了破伤风报告病例和死亡的下降。 全美50个州都对儿童入学前至少接种基本剂量(3剂)的破伤风类毒素作出了法定要求。2002年,全国免疫调查结果表明94％的19-35月龄的儿童都已接种了3剂
Since 1940, the reported rates of tetanus and tetanus-related deaths have been gradually decreasing. This is primarily due to the vaccination of tetanus toxoid [ie, diphtheria children, tetanus toxoid and whole-cell pertussis vaccine (DTP), diphtheria children, tetanus toxoid and acellular pertussis vaccine (DTaP), diphtheria children and tetanus Toxoid (DT), and adult tetanus and diphtheria toxoid (Td)]. However, improved wound management and delivery procedures have also caused a decline in reported cases of tetanus and death. All 50 states have statutory requirements for children who have received at least the basic dose (3 doses) of tetanus toxoid prior to enrollment. In 2002, the national immunization survey showed that 94% of children aged 19-35 months had been vaccinated with 3 doses