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目的观察莫沙必利联合地西泮治疗功能性消化不良的疗效。方法将80例功能消化不良患者随机分为两组:治疗组40例,给予莫沙必利及小剂量地西泮联合用药治疗;对照组40例,单用莫沙必利治疗。比较观察两组的餐后胀满、早饱、上腹部疼痛、上腹部烧灼感等症状的变化。结果用药4周后,治疗组治疗总有效率为87.5%,对照组为67.5%,两组相比,差异有显著性意义(P<0.05)。两组患者均无严重的不良反应。结论莫沙必利联合小剂量地西泮治疗功能性消化不良疗效好,患者耐受性好,是一种可靠可行的治疗功能性消化不良的方案。
Objective To observe the efficacy of mosapride combined with diazepam in the treatment of functional dyspepsia. Methods Eighty patients with functional dyspepsia were randomly divided into two groups: 40 in the treatment group, mosapride in combination with low-dose diazepam, 40 in the control group and only mosapride alone. Compare two groups of postprandial fullness, early satiety, upper abdominal pain, upper abdominal burning and other symptoms change. Results After 4 weeks of treatment, the total effective rate was 87.5% in the treatment group and 67.5% in the control group. There was significant difference between the two groups (P <0.05). Two groups of patients without serious adverse reactions. Conclusion Mosapride combined with low-dose diazepam has good curative effect on functional dyspepsia and good patient tolerance. It is a reliable and feasible treatment for functional dyspepsia.