论文部分内容阅读
急性白血病起病急,病情重,发展快,病程一般在6个月内,骨髓与周围血液中以原始和早期幼稚细胞为主。由于白血病在细胞形态、临床表现及对治疗反应上均有高度异质性,为了更好了解疾病的发病机制、病理学特点、临床病程,需要对其进行分类。本文就急性髓系白血病的诊断分型的研究进展做以下综述。1FAB分型标准FAB分型主要根据细胞形态学特征如细胞的大小、胞浆的颗粒性、染色质的粗密、核/浆比等,以判断细胞的成熟度,并根据原始细胞的数量将白血病进行分型,可将急性髓系白血病分为M0～M78个类型。其主要的缺点是:受主观因素
Emergence of acute leukemia, severe illness, rapid development, the course of the disease generally within 6 months, the bone marrow and peripheral blood to naive and early naive cells. As leukemia in cell morphology, clinical manifestations and response to treatment are highly heterogeneous, in order to better understand the pathogenesis of the disease, pathological features, clinical course, need to be classified. In this paper, the diagnosis of acute myeloid leukemia, the progress made in the following review. 1 FAB classification FAB classification based on cell morphological characteristics such as cell size, cytoplasmic granularity, chromatin density, nuclear / plasma ratio, etc., to determine the maturity of cells, and according to the number of primitive cells leukemia For type, acute myeloid leukemia can be divided into M0 ~ M78 types. Its main drawback is: subject to subjective factors