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X 线诊断工作大多依靠造影检查来完成。为改善造影提高诊断正确率,研制优良的造影剂是非常重要的。一个理想的造影剂应具备两个基本条件:显影清晰,无毒。在临床使用中,不同部位的造影检查对造影剂还有不同的要求。如心血管造影时,由于要快速注入大量造影剂,因此造影剂的粘稠度一定要低,对血压影响要小。冠状动脉造影所要求的造影剂,对心肌应无损害,不影响或少影响冠状血流盈。作脑室和脊髓造影的水溶性造影剂,应不影响脑血屏障,对神经组织应无刺激作用。胃肠造影所需之水溶性造影剂服下后应不吸收,在胃肠道
Most of the X-ray diagnosis work depends on the contrast examination. To improve the diagnostic accuracy by improving the imaging, it is very important to develop an excellent contrast agent. An ideal contrast agent should have two basic conditions: clear visualization and non-toxicity. In clinical use, there are different requirements for contrast agents for contrast imaging in different sites. When angiocardiography is performed, because a large amount of contrast agent must be rapidly injected, the consistency of the contrast agent must be low, and the effect on blood pressure must be small. Contrast agents required for coronary angiography should have no damage to the myocardium and should not affect coronary blood flow. The water-soluble contrast agent for intraventricular and myelography should not affect the blood-brain barrier and should have no stimulatory effect on nerve tissue. The water-soluble contrast agent required for gastrointestinal angiography should not be absorbed after serving, in the gastrointestinal tract