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目的 :分析经导管动脉内灌注化疗栓塞术 (TACE)治疗中晚期肝癌的疗效。方法 :对 13例中晚期肝癌患者施行了 2 5台次肝TACE术。在X光机的导引下 ,将导管超选择性插入肝癌的肿瘤供血动脉。经导管灌注甲酰四氢叶酸钙、5氟脲嘧啶、卡铂 (或顺铂 )。丝裂霉素、阿霉素 (或吡柔比星、表阿霉素 )和碘化油乳化后经导管注入。结果 :全部病人肝区疼痛减轻、消失 ,12例食欲改善 ,11例Karnofsky活动状态评分提高 ,10例AFP下降 ,11例瘤体缩小 ,7例瘤体缩小大于 5 0 %。已死亡病例平均生存期 10个月。随访病例平均随访时间 6 .5个月。结论 :经导管动脉内灌注化疗栓塞术治疗中晚期肝癌可以提高病人生存质量 ,延长生存期。
Objective: To analyze the efficacy of transcatheter arterial chemoembolization (TACE) in the treatment of advanced liver cancer. Methods: Twenty-five patients with advanced hepatocellular carcinoma were treated with TACE. Under the guidance of an X-ray machine, the catheter was superselectively inserted into the tumor feeding artery of liver cancer. Transcatheter infusion of calcium folinate, 5-fluorouracil, carboplatin (or cisplatin). Mitomycin, doxorubicin (or pirarubicin, epirubicin) and iodized oil emulsified after catheter injection. RESULTS: All patients had pain relief and disappeared in the liver area, 12 cases had improved appetite, 11 cases had improved Karnofsky activity score, 10 cases had AFP decline, 11 cases had tumor shrinkage, and 7 cases had tumor shrinkage greater than 50%. The average life span of the deaths was 10 months. The average follow-up time of follow-up cases was 6.5 months. Conclusion: Transcatheter arterial infusion chemoembolization for the treatment of advanced liver cancer can improve the quality of life of patients and prolong the survival period.