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目的:探讨重组人脑利钠肽治疗急性失代偿性心力衰竭患者的效果及其对患者生活质量的影响。方法:将80例急性失代偿性心衰患者按照随机数字法分为对照组与观察组,分别采用硝酸甘油与重组人脑利钠肽治疗。比较两组疗效及生活质量。结果:(1)观察组临床总有效率为95.00%,显著高于对照组的75.00%(P<0.05);(2)两组患者治疗后GQOLI-74量表各维度(躯体功能、生活能力、社会功能以及物质生活)评分均分别显著高于治疗前(P<0.05),且观察组患者治疗后上述各维度评分均分别显著高于对照组治疗后(P<0.05)。结论:重组人脑利钠肽治疗急性失代偿性心力衰竭患者的效果显著,可有效改善患者生活质量,应加以推广。
Objective: To investigate the effect of recombinant human brain natriuretic peptide in patients with acute decompensated heart failure and its impact on the quality of life of patients. Methods: Eighty patients with acute decompensated heart failure were divided into control group and observation group according to random number method, and were respectively treated with nitroglycerin and recombinant human brain natriuretic peptide. The curative effect and quality of life of two groups were compared. Results: (1) The total clinical effective rate in the observation group was 95.00%, which was significantly higher than that in the control group (75.00%, P <0.05); (2) The dimensions of GQOLI-74 after treatment , Social function and material life were significantly higher than those before treatment (P <0.05). The score of each dimension in the observation group after treatment was significantly higher than that of the control group after treatment (P <0.05). Conclusion: The recombinant human brain natriuretic peptide is effective in treating patients with acute decompensated heart failure, which can effectively improve the quality of life of patients and should be promoted.