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目的探讨血清心肌肌钙蛋白Ⅰ在新生儿心肌损伤诊断中的价值。方法选择儿科2010年1月至2011年4月诊治的窒息新生儿40例为实验组,其中轻度窒息24例,重度窒息16例;对照组选择同期40例的正常足月新生儿,进行血清心肌肌钙蛋白Ⅰ检测。结果实验组新生儿轻度、重度窒息患儿的血清肌钙蛋白Ⅰ检测结果均明显高于对照组,两组比较差异显著(P<0.05);实验组患儿7天后血清肌钙蛋白Ⅰ含量明显降低,轻度窒息患儿组7 d后恢复正常,而重度窒息患儿7 d后血清肌钙蛋白Ⅰ高于对照组(P<0.05);新生儿窒息患儿中血清心肌肌钙蛋白Ⅰ阳性率为47.5%,心肌损伤阳性率为75.00%,非心肌损伤阳性率占6.25%。结论血清心肌肌钙蛋白Ⅰ是反映心肌损伤的最佳标志物。
Objective To investigate the value of serum cardiac troponin I in the diagnosis of neonatal myocardial injury. Methods A total of 40 neonates with asphyxia diagnosed and treated by pediatrics from January 2010 to April 2011 were selected as the experimental group, including 24 with mild asphyxia and 16 with severe asphyxia. In the control group, 40 normal newborn infants were enrolled in the study. Serum Cardiac troponin Ⅰ detection. Results The levels of serum troponin I in neonates with mild or severe asphyxia were significantly higher than those in the control group (P <0.05). After 7 days in the experimental group, serum levels of troponin I The level of serum troponin I in children with severe asphyxia was higher than that in the control group (P <0.05). The levels of serum cardiac troponin I in children with asphyxia The positive rate was 47.5%, the positive rate of myocardial injury was 75.00%, and the positive rate of non-myocardial injury was 6.25%. Conclusion Serum cardiac troponin I is the best marker of myocardial injury.