本文目的试图证明小剂量消心痛不能控制的心绞痛大剂量是否仍有效,能否耐受一年之久。 24例患者均有3级劳力性心绞痛;血管造影至少有一主枝血管狭窄超过50％;对小剂量(40毫克/日)消心痛效果不好。研究分三阶段,最初服安慰剂4周,随后6周换用消心痛,每日4次,每次15毫克,每二周增加药量一倍,最后为长时间阶段,剂量增至120毫克/次,维持一年。全部患 The purpose of this article is to demonstrate whether high doses of angina pectoris that are not controlled by small doses of resolving heartburn are still effective and can survive for a year. Twenty-four patients had grade 3 angina pectoris; angiography had at least 50% stenosis in one of the main branches of the vessel; and heart failure with a small dose (40 mg / day) did not work well. The study was divided into three phases, the first placebo for 4 weeks, followed by 6 weeks to use Xiao Xiao Tong, 4 times a day, each 15 mg twice a week to increase the dose doubled, and finally for the long period of time, the dose increased to 120 mg / Times, for one year. All patients