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目的通过调查了解维吾尔族孕妇不同孕期血浆同型半胱氨酸(Hcy)水平及其变化规律,为深入研究孕妇营养与健康状况提供依据。方法以261例维吾尔族孕妇为调查对象,采用连续3 d 24 h膳食回顾法调查孕妇膳食营养素摄入状况;采用酶免疫检测法测定孕妇不同孕期血浆同型半胱氨酸水平。结果被调查维吾尔族孕妇的每日摄入的营养素中,碘、钙、铁、锌、维生素B1、维生素B2、维生素C的每日摄入量分别为105.37μg(占52.69%)、585.37mg(占58.53%)、27.92 mg(占79.77%)、12.54 mg(占76%)、1.19 mg(占73.10%)、1.15 mg(占67.60%)、53.60mg(占41.42%),维生素B12、叶酸的每日摄入量分别为1.33 mg(占51.20%)、123.65μg(占23.95%),其余的营养素摄入量均达到推荐供给量标准;不同孕期血浆同型半胱氨酸平均水平(16.86±4.92)μmol/L;孕早期(16.89±4.83)μmol/L和孕中晚期(16.83±5.01)μmol/L血浆同型半胱氨酸水平比较以及高同型半胱氨酸血症(HHcys)检出率比较,差异均无统计学意义(P﹥0.05)。结论被调查的维吾尔族孕妇膳食结构不合理,其中能量、蛋白质、磷、钠、硒、维生素A、烟酸摄入量偏高,钙、碘、铁、锌、维生素B1、维生素B2、维生素C不足,尤其是与Hcy代谢相关的维生素B12和叶酸的摄入量严重不足。各孕期血浆同型半胱氨酸水平均偏高。
Objective To investigate the level of plasma homocysteine (Hcy) and its variation during pregnancy in Uyghur pregnant women through surveys, so as to provide basis for further study on the nutrition and health status of pregnant women. Methods A total of 261 Uyghur pregnant women were enrolled in this study. Dietary intakes of pregnant women were investigated by 24-hour continuous dietary recall for 3 days. Plasma homocysteine level was measured by enzyme immunoassay. Results The daily intake of iodine, calcium, iron, zinc, vitamin B1, vitamin B2 and vitamin C in Uyghur pregnant women was 105.37μg (52.69%) and 585.37mg Accounting for 58.53%), 27.92 mg (accounting for 79.77%), 12.54 mg accounting for 76%, 1.19 mg accounting for 73.10%, 1.15 mg accounting for 67.60%, 53.60 mg accounting for 41.42%, vitamin B12, folic acid The daily intakes were 1.33 mg (51.20%) and 123.65μg (23.95%), respectively. The other nutrient intake reached the recommended level. The average plasma homocysteine level in different pregnancy (16.86 ± 4.92 ) micromol / L in the first trimester of pregnancy (16.89 ± 4.83) μmol / L and the second trimester (16.83 ± 5.01 micromol / L) plasma homocysteine and the detection rate of homocysteine (HHcys) There was no significant difference between the two groups (P> 0.05). Conclusion The dietary structure of Uighur pregnant women surveyed is unreasonable. The intake of energy, protein, phosphorus, sodium, selenium, vitamin A and nicotinic acid are high, while calcium, iodine, iron, zinc, vitamin B1, vitamin B2, vitamin C Inadequate, especially with the metabolism of Hcy vitamin B12 and folic acid intake is seriously inadequate. Plasma homocysteine levels during pregnancy were high.