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本文采用放射免疫法对 6 9例围产期窒息儿于出生 12小时内进行了血清胃泌素、胃动素、血管活性肽水平测定 ;将 34例窒息 组患儿于生后 1周内给予非肠道内喂养 ,35例窒息 组患儿于出生 2 4小时后及窒息 组出生 1周后给予部分或全部肠道内喂养 ,并进行三种胃肠激素的动态观察。结果出生 12小时内窒息组胃肠激素水平明显高于 6 0例足月健康儿 (对照组 ) ,有显著性差异 ;窒息 组生后第 4、7天三种胃肠激素水平均低于对照组 (除第 4天胃动素外 ,均有统计学意义 ) ;窒息 组生后第 4、7、10天以及窒息 组生后第 10天 ,三种胃肠激素水平与对照组无明显差异性。提示 ,围产期窒息患儿血中胃泌素、胃动素、血管活性肽明显增高 ;窒息复苏后胃肠激素水平与喂养方式直接有关。肠道内喂养可促进胃肠激素的分泌。因此 ,对窒息儿尽早喂养的方法有待讨论
In this paper, 69 cases of perinatal asphyxia were measured by radioimmunoassay in serum gastrin, motilin and vasoactive peptide levels within 12 hours of birth; 34 cases of asphyxia group were given within 1 week after birth Parenteral feeding, 35 asphyxia children after birth 24 hours and 1 week after birth asphyxia were given part or all of the gut fed, and the dynamic observation of three gastrointestinal hormones. Results The level of gastrointestinal hormone in asphyxia group was significantly higher than that in 60 healthy full-term children (control group) within 12 hours of birth, and the levels of three gastrointestinal hormones in asphyxia group were lower than those in control group (Except for motilin on day 4, all of which were statistically significant). There was no significant difference in the levels of three gastrointestinal hormones between the 4th, 7th and 10th days after asphyxia group and the 10th day after birth asphyxia group Sex. Tip, perinatal asphyxia children with gastrin, motilin, vasoactive peptide was significantly higher; asphyxia resuscitation gastrointestinal hormone levels and feeding directly related. Intestinal feeding can promote the secretion of gastrointestinal hormones. Therefore, the method of asphyxial feeding as soon as possible to be discussed