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茯苓Poria cocos(Schw.)自古就是食用与药用珍品,是传统中药的“四君八珍”之一,《神农本草经》把它列为上品。茯苓具有利水渗湿、健脾宁心的功效。但是,占茯苓菌核93％的β-茯苓聚糖无抗肿瘤作用,用化学方法处理β-茯苓聚糖后,才能使之转化成为羧甲基茯苓多糖(Carboxymethylpachymaran)。笔者1979年成功地研制出羧甲基茯苓多糖,药理试验证明,具有抗肿瘤,免疫调节,保肝降谷丙转氨酶,减轻放射副作用,间接抗病毒,诱生和促诱生干拢素与白细胞介素的作用。毒理试验证明,羧甲基茯苓多糖无毒性,无致畸致突变结果。本文报道羧甲基茯苓多糖的药用。 一、临床试验用药方法 羧甲基茯苓多糖精制成注射剂,符合中国药典各项规定,每安瓿2ml 30mg。临床试验用药方法如下:治疗慢性肝炎病人,每日肌肉注射2次,每次60mg,30日为一个疗程,连用两个疗程。治疗癌症病人,每日肌肉注射2次,每次60mg,或每日120～150mg渗入10％葡萄糖生理盐水500ml静脉滴注,30日为一个疗程,连用两个疗程。
茯苓Poria cocos (Schw.) has been a food and medicinal treasure since ancient times and is one of the “four monarchs and eight treasures” of traditional Chinese medicine. The “Shen Nong Ben Cao Jing” has listed it as a top grade.茯苓 茯苓 利 利 利 利 茯苓 茯苓 茯苓 茯苓 茯苓 茯苓 茯苓 茯苓 茯苓 茯苓 茯苓 茯苓 茯苓 茯苓 茯苓 茯苓 茯苓 茯苓 茯苓 茯苓 茯苓 茯苓. However, 93% of the sclerotia of β-sulphate has no anti-tumor effect. After chemical treatment of β-sulphocan, it can be transformed into Carboxymethylpachymaran. The author successfully developed carboxymethyl guanosine polysaccharide in 1979, and proved by pharmacological experiments that it has anti-tumor, immune regulation, hepatoprotective glutamic-pyruvic transaminase, reduce radiation side effects, indirect antiviral, induce and promote induction of lectin and leukocytes. The role of interleukins. Toxicological tests have shown that carboxymethyl guanosyl polysaccharide is non-toxic and has no teratogenic mutagenesis results. This article reports the medicinal use of carboxymethylhydrazine polysaccharides. First, the clinical test drug method Carboxymethyl guanosine refined into injections, in line with the provisions of the Chinese Pharmacopoeia, each ampoules 2ml 30mg. The methods of clinical trials are as follows: In the treatment of patients with chronic hepatitis, intramuscular injection twice daily, each 60 mg, 30 days for a course of treatment, use two courses. Treatment of cancer patients, intramuscular injection twice daily, 60mg each time, or 120-150mg per day infiltration of 10% glucose 500ml intravenous infusion, 30 days for a course of treatment, use two courses.