许多糖尿病患者需要胰岛素治疗,尽管有很好的效果,但在代谢平衡中仍不可避免有很大的波动。这些病人因发生高血糖症或低血糖症,每年不得不多次送进医院或糖尿病诊疗所去医治。一个健康人血糖浓度波动于60～130毫克％之间。如果血糖有轻度升高,胰岛β细胞会立即增加胰岛素的分泌,血糖浓度又降至100毫克％以下。胰岛素的短半衰期约为10分钟,当血糖浓度升高时,几秒钟内即可促进胰岛素分泌,因此有可能使这种内环境 Many people with diabetes require insulin therapy, and despite good results, there is inevitably a great deal of volatility in the metabolic balance. These patients have to be admitted to a hospital or a diabetes clinic several times a year for treatment of hyperglycemia or hypoglycemia. A healthy person’s blood glucose concentration fluctuates between 60 and 130 mg%. If there is a slight increase in blood glucose, pancreatic β cells immediately increase insulin secretion, blood glucose levels dropped to 100 mg% or less. The short half-life of insulin is about 10 minutes, and as the blood sugar level rises, it promotes insulin secretion in a matter of seconds, making it likely that this internal environment