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目的：通过对足月新生儿缺氧缺血性脑病（ＨＩＥ）的ＭＲＩ分析，找出ＨＩＥ的ＭＲＩ特点。材料和方法：对４５例临床确诊为ＨＩＥ的足月新生儿行ＭＲ检查。采用０．３５Ｔ磁共振仪，选自旋回波序列（ＳＥ），在Ｔ１ＷＩ及Ｔ２ＷＩ上对脑皮层及皮层下白质，深部白质；基底节及丘脑；脑室及蛛网膜下腔等部位进行观察。结果：在Ｔ１ＷＩ上见皮层沿脑回分布点的及条状高信号，深部白质沿侧室壁的条状高信号，基底节及丘脑高信号，幕上及幕下蛛网膜下腔出血呈现的高信号，其发生率分别为８４．４４％，３７．７８％，４２．２２％，１３．３３％与４８．８９％。此外，额叶深部白质内对称的点状高信号也相当特殊，发生率４４．４４％，其它改变有皮层下坏死软化，占２０％，脑室内出血占８．８９％。结论：本文主要描述了足月新生儿ＨＩＥ的ＭＲＩ特点并对其相关的病理基础进行探讨。
Objective: To identify MRI features of HIE through MRI analysis of full-term neonatal hypoxic-ischemic encephalopathy (HIE). MATERIALS AND METHODS: MR examinations were performed on 45 neonates with full-term clinical diagnosis of HIE. Using 0.35T magnetic resonance apparatus, selected from the spin echo sequence (SE), T1WI and T2WI on the cortex and subcortical white matter, deep white matter; basal ganglia and thalamus; ventricular and subarachnoid and other parts were observed. RESULTS: On T1WI, there was a high signal of cortical distribution along the cerebral gyrus and a stripe-shaped signal. The stripe-shaped high signal of the deep white matter along the lateral wall, the basal ganglia and the high signal of the thalamus, and the supratentorial subarachnoid hemorrhage , The incidence rates were 84.44%, 37.78%, 42.22%, 13.33% and 48.89% respectively. In addition, the symmetrical spot-like high signal in the deep frontal white matter was quite special, with a rate of 44.44%. Other changes included subcutaneous cortical softening, accounting for 20% and intraventricular hemorrhage accounting for 8.89%. Conclusion: This article describes the MRI features of full-term neonates with HIE and its related pathological basis.