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本文报道了用间接免疫荧光检测人体利什曼病、小鼠热带利什曼感染、豚鼠L. enriettii感染的抗体结果。在豚鼠感染L. enriettii 12天时,间接免疫荧光在1/64滴度时即可检出抗体。在感染过程中直至约76天损害达顶点时抗体的滴度和强度均持续上升。损害愈合过程中及其后,从76天起抗体滴度即下降1～2个稀释度。正常对照豚鼠的抗体滴度为0～1/16。有转移病变的动物,抗体滴度一直很高。且在较低的滴度时荧光很强。在小鼠感染热带利什曼后23天,1/64滴度即可检出抗体。在感染过程中,抗体滴度和荧光强度有所上升,在感染后94天,抗
This article reports the results of an indirect immunofluorescence assay for leishmaniasis in humans, tropical Leishmania infection, and L. enriettii infection in guinea pigs. At 12 days after guinea pig infection with L. enriettii, indirect immunofluorescence detected antibodies at 1/64 titers. Antibody titers and intensities continued to increase up to about the 76th day of damage during infection. During and after the healing of the lesion, the titer of the antibody decreased from 1 to 2 dilutions from 76 days. Antibody titers in normal control guinea pigs ranged from 0 to 1/16. In animals with metastatic disease, antibody titers have been high. And at lower titers fluorescence is very strong. Antibody was detected at 1/64 titer 23 days after infection with Leishmania in mice. Antibody titers and fluorescence intensities increased during infection, and were 94 days after infection