采用硅烷偶联剂对生物活性玻璃(BG)进行表面修饰以改善其与高分子的亲和性。通过溶胶凝胶法制得BG,将氨丙基三乙氧基硅烷(APTES)键连到BG表面,采用FTIR、TG、激光粒度仪等对修饰前后的BG进行表征,并通过细胞实验对材料的细胞相容性进行初步研究。结果表明,修饰后BG的FTIR图谱上出现归属于C—H的伸缩振动吸收峰,在DTG曲线上观察到明显的有机基团燃烧失重峰,表明APTES接枝到生物玻璃表面;而MC-3T3细胞增殖测定和SEM结果显示经表面修饰后的BG更有利于细胞的生长增殖。 Surface modification of bioactive glass (BG) with silane coupling agents to improve its affinity with polymers. BG was prepared by sol-gel method, aminopropyltriethoxysilane (APTES) was bonded to the BG surface, and the BG before and after modification was characterized by FTIR, TG, laser particle size analyzer. Cell compatibility for a preliminary study. The results showed that there was a stretching vibration absorption peak assigned to C-H on the FTIR spectrum of BG, and a significant weight loss peak of organic group was observed on the DTG curve, indicating that APTES was grafted to the surface of the bioglass. However, MC-3T3 Cell proliferation assay and SEM results showed that the surface modified BG is more conducive to cell growth and proliferation.