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目的观察肌肉注射苯海拉明针治疗甲氧氯普胺(胃复安)所致锥体外系综合征的效果。方法选择我院急诊留观病例,60例均为应用胃复安后引起的锥体外系统症状,随机分为治疗组和对照组各30例。治疗组用苯海拉明针20mg/次肌肉注射,每日1～2次;对照组应用地西泮针10mg/次肌肉注射,每日1～2次,两组都同时采取输液、利尿等综合治疗措施。结果治疗组显效17例,有效11例,无效2例,总有效率为93.33%;对照组显效9例,有效12例,无效9例,总有效率为70.00%。结论治疗组疗效高于对照组,苯海拉明针优于地西泮针,苯海拉明对锥体系统综合征有良好的治疗效果。
Objective To observe the effect of intramuscular injection of diphenhydramine injection on metoclopramide (metoclopramide) induced extrapyramidal syndrome. Methods Selected cases of emergency observation in our hospital, 60 cases were caused by the application of metoclopramide extrapyramidal symptoms were randomly divided into treatment group and control group of 30 cases. The treatment group with diphenhydramine injection of 20mg / times intramuscularly, 1 or 2 times a day; control group with diazepam 10mg / intramuscular injection, 1 or 2 times a day, both groups also take infusion, diuretic, etc. Comprehensive treatment. Results In the treatment group, 17 cases were markedly effective, 11 cases were effective, 2 cases were ineffective, and the total effective rate was 93.33%. In the control group, 9 cases were markedly effective, 12 cases were effective and 9 cases were ineffective. The total effective rate was 70.00%. Conclusion The curative effect of the treatment group is higher than that of the control group, diphenhydramine needle is better than that of diazepam, and diphenhydramine has a good therapeutic effect on pyramidal syndrome.