对７例食管溃疡患者行全胸段或中下段食管切除食管胃套入式端侧吻合术，术后无吻合口瘘等并发症，远期效果良好。作者认为，外源性理化因素破坏食管粘膜及减弱其修复能力是形成溃疡的重要因素。对溃疡＞１ｃｍ、位于胸中段、有重度鳞状上皮不典型增生及恶变者应施行手术治疗。手术宜采用彻底切除病变并抗返流的术式。 Seven patients with esophageal ulcer underwent thoracic or mid-lower esophageal resection of esophagogastric end-to-side anastomosis without postoperative complications such as anastomotic fistula, the long-term effect is good. The authors believe that exogenous physicochemical factors that destroy the esophageal mucosa and reduce its ability to repair is an important factor in the formation of ulcers. On the ulcer> 1cm, located in the middle of the chest, with severe squamous dysplasia and malignant transformation should be implemented surgery. Surgery should be used to completely remove the disease and anti-reflux surgery.