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目的对比老年人(72～94岁)中冠心病合并高尿酸血症患者与单纯冠心病患者静息心电图提示坏死、损伤、缺血的QRS-T改变,以了解老年冠心病合并高尿酸血症的静息心电图表现。方法选择2003年7月至2010年12月住院的患有冠心病老年人中的204例为研究对象,采用酶法在日立7600生化分析仪上测定静脉血尿酸,以血尿酸≥420μmol/L为界限,分为2组,其中160例尿酸正常,44例患有高尿酸血症。比较分析冠心病合并高尿酸血症组与冠心病尿酸正常组的静息12导心电图中提示坏死、损伤、缺血的QRS-T改变。结果随着年龄的增大,204例患者的血尿酸水平及心电图异常率均呈递升(P均<0.05)。高尿酸血症组冠心病患者的静息心电图异常率明显高于血尿酸正常组(86.4%vs75.6%,P<0.05)。结论老年冠心病合并高尿酸血症患者静息心电图的改变较老年冠心病血尿酸正常患者明显。
Objective To compare the QRS-T changes of necrosis, injury and ischemia induced by resting electrocardiogram in elderly patients (72-94 years) with coronary heart disease complicated with hyperuricemia and simple coronary heart disease, so as to understand the relationship between senile coronary heart disease complicated with hyperuricemia Resting electrocardiogram performance. Methods Totally 204 elderly patients with coronary heart disease hospitalized from July 2003 to December 2010 were enrolled in this study. Enzymatic determination of uric acid was performed on a Hitachi 7600 biochemical analyzer. Serum uric acid ≧ 420 μmol / L Boundaries, divided into two groups, of which 160 cases of normal uric acid, 44 cases of hyperuricemia. Comparative analysis of coronary heart disease with hyperuricemia group and coronary heart disease uric acid normal resting 12-lead ECG tips of necrosis, injury, ischemic QRS-T changes. Results With the increase of age, the blood uric acid level and abnormal rate of electrocardiogram increased in 204 patients (all P <0.05). The abnormal ECG rate of resting ECG in patients with hyperuricemia was significantly higher than that of patients with normal serum uric acid (86.4% vs 75.6%, P <0.05). Conclusion The changes of resting electrocardiogram in elderly patients with coronary heart disease complicated with hyperuricemia are more obvious than those with normal blood uric acid in elderly patients with coronary heart disease.