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目的检测HIV/AIDS与肺结核病人的CD4+、CD8+细胞的变化。方法流式细胞计数仪检测CD4+、CD8+T淋巴细胞,用双侧t检验进行统计。结果HIV/AIDS与肺结核患者存在以CD4T淋巴细胞下降为突出表现的细胞免疫受损,HIV/AIDS的CD4+细胞降低明显高于肺结核病人,HIV/AIDS的CD8+细胞升高明显高于肺结核病人。结论HIV/AIDS与肺结核病人都存在着不同程度的CD4+T淋巴细胞异常,CD4+T细胞是HIV/AIDS重要指标;CD4+T细胞对肺结核病人是用来估计机体的免疫状态或是一个指标,但不是一个绝对指标。CD4+T细胞和CD8+T细胞与肺结核病的类型及病情的变化、预后的关系需要进一步研究。
Objective To detect the changes of CD4 +, CD8 + cells in HIV / AIDS and tuberculosis patients. Methods Flow cytometry was used to detect CD4 +, CD8 + T lymphocytes and statistics were performed by two-tailed t-test. Results The HIV / AIDS and tuberculosis patients suffered from the decline of CD4 T lymphocytes. The decrease of HIV / AIDS CD4 + cells was significantly higher than that of pulmonary tuberculosis patients. The HIV / AIDS CD8 + cells were significantly higher than those of pulmonary tuberculosis patients. Conclusion CD4 + T cells are important indicators of HIV / AIDS in patients with HIV / AIDS and pulmonary tuberculosis. CD4 + T cells are used to estimate the immune status or an index , But not an absolute indicator. The relationship between CD4 + T cells and CD8 + T cells and tuberculosis type and disease, prognosis need further study.