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A 54-year-old man was hospitalized with severe chest pain,spreading to the back and abdomen continuously for 6 hours. He was diagnosed as aortic dissection aneurysm type Ⅰ and treated with intravenous infusion of sodium nitroprusside 100mg by speed of 150μg/min.5 days later,the patient developed mild restless while his BP was 150/96mmHg.Then he was treated with intravenous infusion of sodium nitroprusside 150mg by speed of 200μg/min.His BP was 120/80mmHg, and the patient developed mania, euphoria, incoherent speech, visual and auditory hallucination, abnormal behavior and refusal of all the treatments on no purpose. The symptoms lessened after withdrawal of sodium nitroprusside for 12 hours. 24 hours later, his symptoms were resolved completely. There were no mental disorders to occurr with taking other antihypentensive drugs.
A 54-year-old man was hospitalized with severe chest pain, spreading to the back and abdomen continuously for 6 hours. He was diagnosed as aortic dissection aneurysm type I and treated with intravenous infusion of sodium nitroprusside 100 mg by speed of 150 μg / min. 5 days later, the patient developed mild restless while his BP was 150/96 mmHg.Then he was treated with intravenous infusion of sodium nitroprusside 150 mg by speed of 200 μg / min. His BP was 120/80 mmHg, and the patient developed mania, euphoria, incoherent speech, visual and auditory hallucination, abnormal behavior and refusal of all the treatments on no purpose. The symptoms lessened after withdrawal of sodium nitroprusside for 12 hours. 24 hours later, his symptoms were resolved completely. taking other antihypentensive drugs.