脑性瘫痪是在小儿出生前至出生后脑发育阶段各种原因造成的非进行性脑损伤综合征,是小儿致残的主要疾病之一~([1])。脑性瘫痪对人的长期严重危害依然未得到很好的解决,是一种防治极为困难和高致残率的脑损伤综合征~([1])。我国小儿脑性瘫痪的发病率为3‰~5‰~([2])。各种围生期因素引起的缺氧和脑血流减少或暂停均可导致胎儿和新生儿出现脑损伤,尤其易发生缺氧缺血性脑病,进而导致脑性瘫痪等。脑性瘫 Cerebral palsy is a non-progressive brain injury syndrome caused by a variety of causes from childhood birth to postnatal brain development and is one of the major disorders of pediatric disability (1). Long-term serious harm to people’s cerebral palsy is still not been well solved, and it is a kind of brain injury syndrome with extremely difficult and high morbidity rate [1]. The incidence of cerebral palsy in children in our country is 3 ‰ ~ 5 ‰ ~ ([2]). A variety of perinatal factors caused by hypoxia and cerebral blood flow reduction or suspension can lead to fetal and neonatal brain injury, especially prone to hypoxic-ischemic encephalopathy, leading to cerebral palsy and so on. Cerebral palsy