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已有报道,去除供者骨髓中的CD_6~-细胞,可减少HLA相容的异基因骨髓移植中的移植物抗宿主反应,而又不影响移植效果.作者建立的免疫磁性珠细胞分离技术,是用抗CD_6致敏的单个核细胞与过量的结合羊抗鼠球蛋白抗体的超顺磁性珠混合成悬液,4℃离心后加入吖啶
It has been reported that the removal of CD_6 ~ - cells in donor bone marrow can reduce the graft-versus-host reaction in HLA-compatible allogeneic bone marrow transplantation without affecting the transplantation effect.The immunomagnetic bead- Is anti-CD_6 sensitized mononuclear cells and excess conjugated goat anti-mouse globulin antibody superparamagnetic beads mixed into a suspension, after 4 ° C was added acridine